Plant lettuce in compost-rich, well-draining soil. Lettuce does best when planted directly from seed.
To plant lettuce from seed, plant seeds every ½” or so and lightly cover with soil. Do not let seeds dry out until they germinate. Thin seedlings (enjoy them as baby greens) until leaf lettuce is about 4” apart, head lettuce is 12” apart, and romaine and butterhead lettuce is 6”-8” apart